Summary
This Clinical Evidence delves into the most recent real-world data concerning the performance of the HeartLogic™ algorithm and S-ICD and their potential application in clinical practice to improve patient outcomes. A new re-validation of the HeartLogic diagnostic tool¹ is explored in order to confirm the performance of the algorithm in clinical practice for implantable cardioverter defibrillators (ICD) and cardiac resynchronization therapy devices (CRT-D). S-ICD clinical experiences from two retrospective analyses from the observational Rhythm Detect registry are described. One analysis assesses the enhanced outcomes associated with placing the S-ICD generator in the intermuscular space²; the other investigates the decrease in inappropriate therapies through device programming³.
Key Takeaways
- HeartLogic Algorithm: Real-World Validation:
HeartLogic performances were validated in a real-world setting: high performance in terms of sensitivity and false positive rate were confirmed for ICD and CRT-D patients¹. - S-ICD Performance in Real-World Practice 1:
Placing the S-ICD generator in the intermuscular space instead of the standard subcutaneous pocket results in fewer device-related complications and inappropriate shocks over a medium-term follow-up² . - S-ICD Performance in Real-World Practice 2:
In clinical practice, there has been a trend in recent years towards the wider adoption of optimized programming. The standardised programming proposed by the UNTOUCHED study reduced the rate of inappropriate shock in the S-ICD population, without affecting therapy effectiveness³.
Gain deeper insights by downloading the full newsletter
![Stimview XT data driven brochure](/en-EU/medical-specialties/electrophysiology/clinical-evidence-newsletter/2024/1/_jcr_content/root/container/container_947831390/container_1510545751/container_1773509255/container/image_copy.coreimg.png/1710865088010/new-banner-thumbnail-for-webpage-1---copy.png)