Cryoablation for the treatment of renal cell carcinoma

Kidney Cancer is one of the most common types of cancer and usually affects adults in their 60s/70s. 

More than 90% of kidney cancer diagnoses are renal cell carcinoma (RCC).

90%

Mortality incidence of kidney cancer1

Due to the increasing incidence of renal cell carcinoma in recent years, particular attention has been directed towards cryoablation as cancer’s treatment.

Want to learn more about the clinical data available on cryoablation vs partial nephrectomy?

Discover the latest clinical data on cryoablation for RCC 

RCC

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Kidney Ablation

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Large studies show comparable oncological outcomes to surgery, with fewer complications and a shorter hospital stay. [2]

Recently, cryoablation has been increasingly recognised by urologists, oncologists, and interventional radiologists as a preferred treatment for RCC.  Indeed, percutaneous cryoablation is now endorsed by the European Association of Urology (EAU) as a highly effective technique in terms of success rates (> 95%)3, particularly in patients with stage 1a or 1b RCC3, 4, 5.

Renal Cell Carcinoma
EAU Guidelines on Renal Cell Carcinoma
  1. Sung WW, Ko PY, Chen WJ, et al. Trends in the kidney cancer mortality‑to‑incidence ratios according to health care expenditures of 56 countries. Sci Rep 11, 1479 (2021). 10.1038/s41598-020-79367-y
  2. Campbell et al, 2017 RENAL MASS AND LOCALIZED RENAL CANCER: AUA GUIDELINE Escudier B, Porta C, Schmidinger M, Rioux-Leclercq N, Bex A, Khoo V, Grünwald V, Gillessen S, Horwich A; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org. Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up†. Ann Oncol. 2019 May 1;30(5):706-720. doi: 10.1093/annonc/mdz056. PMID: 30788497.
  3. Ljungberg B, Albiges L, Bedke J, et al. (2021). European Association of Urology Guidelines on Renal Cell Carcinoma 2021. 
    https://www.researchgate.net/publication/350621384_European_Association_of_Urology_Guidelines_on_Renal_Cell_Carcinoma_2021
  4. Morkos J, Porosnicu Rodriguez KA, Zhou A, et al. Percutaneous Cryoablation for Stage 1 Renal Cell Carcinoma: Outcomes from a 10-year Prospective Study and Comparison with Matched Cohorts from the National Cancer Database. Radiology 2020; 296:452–459. doi: 10.1148/radiol.2020192325
    10.Maria T, Georgiades C. Percutaneous Cryoablation for Renal Cell Carcinoma. J Kidney Cancer VHL. 2015;2(3):105-113. doi: 10.15586%2Fjkcvhl.2015.34
  5. Campbell et al, 2017 RENAL MASS AND LOCALIZED RENAL CANCER: AUA GUIDELINE Escudier B, Porta C, Schmidinger M, Rioux-Leclercq N, Bex A, Khoo V, Grünwald V, Gillessen S, Horwich A; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org. Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up†. Ann Oncol. 2019 May 1;30(5):706-720. doi: 10.1093/annonc/mdz056. PMID: 30788497.