References:
1. Okun MS et al. 2024. Real-World Outcomes in USA using DBS Systems with Directionality and Multiple Independent Current Control [Abstract]. North American Neuromodulation Society (NANS), Las Vegas, NV; Jan 18 - 21, 2024.
2. Aubignat, M., Berro, A., Tir, M., & Lefranc, M. (2024). Imaging-Guided Subthalamic Nucleus Deep Brain Stimulation Programming for Parkinson Disease. Neurology Clinical Practice, 14(6). https://doi.org/10.1212/cpj.0000000000200326
3. Ojukwu, D. I., Wang, A. R., Hornbeck, T. S., Lim, E. A., Sharrard, J., Dhall, R., Buch, V. P., & Halpern, C. H. (2022). Conversion to Hybrid Deep Brain Stimulation System to Enable Multi‐Contact Fractionation Can be Therapeutic. Movement Disorders, 37(6), 1321-1323. https://doi.org/10.1002/mds.29007.
4. April 2020 – Footprint defined as volume + thickness. Data on file. at Boston Scientific Corporation. Compared to all EU commercially available DBS IPG's from 2010 onwards.
5. Torres V, 2024, npj Parkinson’s Disease https://doi.org/10.1038/s41531-024-00639-9
6. Timmermann L et. al. Multiple-source current steering in subthalamic nucleus deep brain stimulation for Parkinson’s disease (the VANTAGE study): a non-randomised, prospective, multicentre, open-label study. Lancet Neurol. 2015 Jul;14(7):693-701.
7. A. Rezaei Haddad, M. Samuel, N. Hulse, H. Y. Lin, and K. Ashkan, “Long-Term Efficacy of Constant Current Deep Brain Stimulation in Essential Tremor,” Neuromodulation, vol. 20, no. 5, pp. 437–443, 2017, doi: 10.1111/ner.12592.
8. Steffen, J. K., Reker, P., Mennicken, F. K., Dembek, T. A., Dafsari, H. S., Fink, G. R., Visser-Vandewalle, V., & Barbe, M. T. (2020). Bipolar Directional Deep Brain Stimulation in Essential and Parkinsonian Tremor. Neuromodulation: Technology at the Neural Interface, 23(4), 543–549. DOI: 10.1111/ner.13109
9. Reker, P., Dembek, T. A., Becker, J., Visser-Vandewalle, V., & Timmermann, L. (2016). Directional deep brain stimulation: A case of avoiding dysarthria with bipolar directional current steering. Parkinsonism & Related Disorders, 31, 156-158. https://doi.org/10.1016/j.parkreldis.2016.08.007
10. Kirsch, A. D., Hassin-Baer, S., Matthies, C., Volkmann, J., & Steigerwald, F. (2018). Anodic versus cathodic neurostimulation of the subthalamic nucleus: A randomized-controlled study of acute clinical effects. Parkinsonism & Related Disorders, 55, 61-67. https://doi.org/10.1016/j.parkreldis.2018.05.015
Results from case studies are not necessarily predictive of results in other cases. Results in other cases may vary.
CAUTION: The law restricts these devices to sale by or on the order of a physician. Indications, contraindications, warnings, and instructions for use can be found in the product labelling supplied with each device or at www.IFU-BSCI.com. Products shown for INFORMATION purposes only and may not be approved or for sale in certain countries. This material not intended for use in France.
