Clinical Evidence
“In a retrospective study, clipping polypectomy sites closed after endoscopic resection of large sessile and flat colorectal lesions was associated with a reduced incidence of delayed postpolypectomy bleeding.”1
“The delayed hemorrhage rate was 9.7% in the not clipped group versus 1.8% in the fully clipped group.”1
“Polyps that were not clipped were 4.4 times more likely to have any complications (1.8, 10.9; P = .001) compared with polyps that were completely clipped.”1
“[A]voidance of unnecessary surgical resection of endoscopically removable polyps is another potential cost-savings associated with prophylactic clip closure of large polyp sites, if the availability of clip closure increases rates of endoscopic resection because of decreased fear of complications.”1