OPTALYSE long-term data
Sustained RV remodeling & improved patient outcomes
In the OPTALYSE study which evaluated the optimal dose/duration of EKOS treatment, patients were followed for one year. In addition to showing quick improvement in RV function, the long-term data showed sustained RV remodeling out to one-year. OPTALYSE was also the first study of an interventional pulmonary embolism (PE) treatment to show improvement in patient quality of life outcomes.1
RV function
RV/LV ratio continued to reduce after 48h
p value <030001@365d
Endurance
Mean 6-minute walk test distance
Physical functioning
Mean PROMUS-PF-6b scores
Quality of life
Mean PEmb-QOL scores
1. Tapson V et al. A randomized trial of the optimum duration of acoustic pulse thrombolysis procedure in acute intermediate-risk pulmonary embolism. JACC: Cardiovascular Interventions 2018; 11(14):1401-1410.