SAFARI2

SAFARI²™ Pre-Shaped TAVR Guidewire

The SAFARI² Pre-Shaped Guidewire is designed to facilitate stable delivery of devices during transcatheter aortic valve replacement (TAVR) procedures. Its unique pre-shaped double curve design enables atraumatic placement within the left ventricle.
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How it works

The SAFARI2 TAVR guidewire features a double curve architecture that absorbs contractions of the left ventricle and facilitates stable, atraumatic placement of new valves. Available in three curve sizes, the SAFARI2 provides flexibility with options, enabling physicians to choose a size that fits their patients' specific needs and conditions. And with optimized rail support, it has superior shape retention that delivers consistent wire predictability.

Why choose SAFARI² TAVR Guidewire

Superior shape retention and size options provide wire predictability and safety for TAVR procedures

Enhanced wire predictability

The SAFARI2 Pre-shaped wire provides guide wire predictability and superior shape retention.*,†

Largest choice of guidewire sizes

A wide selection of guidewire options with three curve sizes to choose from gives physicians flexibility to fit the patients' needs and conditions.

Streamlined device delivery

Optimized rail support provides streamlined and accurate device delivery for TAVI and TAVR procedures.‡,§,**

Safari's optimized rail support provides streamlined and accurate device delivery for transcatheter aortic procedures.

Designed for superior shape retention

The double curve architecture absorbs contractions of the left ventricle and facilitates stable, atraumatic placement. SAFARI2 demonstrates superior curve retention and maintenance of geometry during compression.*,†

SAFARI2 compression testing

SAFARI2 keeps a stable position and curve when subjected to a 30% compression load simulating the compression in the left ventricle.

Safari guidewire for TAVI and TAVR procedures keeps a stable position and curve when subjected to a 30% compression load.

SAFARI2 curve retention testing

SAFARI2 maintains a high percentage of curve geometry after insertion into a pigtail catheter.

After compression testing, SAFARI2 maintains a high percentage of curve geometry after insertion into a pigtail catheter.

Three sizes for customized selection

  • Pre-shaped design for predictable, reliable performance across a broad spectrum of transcatheter devices*,†, ‡,§,**
  • Widest guidewire choice with three curve sizes, enabling customized selection based on physician preference
  • Extra small curve designed for small and/or hypertrophic ventricles
SAFARI² TAVI Guidewire in multiple curve sizes and options to enable customized selection based on physician preference.

Best-in-class shape retention during compression

SAFARI2 Guidewire demonstrates superior curve retention and maintenance of geometry during compression.

SAFARI² guidewire under compression test showing a stable position when subjected to a 30% load simulating the compression in the left ventricle.
SAFARI2 Guidewire
SAFARI2 Guidewire keeps a stable position and curve when subjected to an equivalent compression load simulating the compression in the left ventricle
Amplatz Super Stiff Guidewire versus Safari Guidewire competitive compression test.
Amplatz Super Stiff™ Guidewire
This deomonstrates the Amplatz Super Stiff Guidewire when subjected to an equivalent compression load simulating the compression in the left ventricle.

Curve retention (%)

In competitive bench testing the SAFARI2 Guidewire outperformed other wires in shape retention, preserving 96% of its original shape after use.

Shape retention vs. competitors

Graph showing Safari Guidewire outperforms competitor wires in shape retention.

Structural heart portfolio

Our portfolio of transcatheter valvular therapies offers more paths to predictable procedures and optimized outcomes.

Bench testing performed by Boston Scientific. Bench test results may not necessarily be indicative of clinical performance. Data on file.

* Curve Retention test data with SAFARI2 Extra Small, Confida™ Brecker, Amplatz Extra Stiff™, and Amplatz Super Stiff™ Guidewires (n = 1).

 † Guidewire Compression test data with SAFARI2 Extra Small, Confida Brecker, Amplatz Extra Stiff, and Amplatz Super Stiff Guidewires (n = 1).

 ‡ Nosecone Tracking test data with SAFARI2 Extra Small, Confida Brecker, Amplatz Extra Stiff, and Amplatz Super Stiff Guidewires (n = 1).

 § Simulated Use Static Friction, Dynamic Friction, and Distal Curve Displacement test data with Lotus™ Valve System with Safari Large and Amplatz Super Stiff Guidewires (n = 4).

 ** Simulated Use Friction, Dynamic Friction, and Distal Curve Displacement with Evolut® R with SAFARI2 Extra Small and Confida Brecker Guidewires (n = 3).

The Safari™ Guidewire is manufactured by Lake Region Medical and distributed by Boston Scientific Corporation.

All cited trademarks are the property of their respective owners. CAUTION: Federal (U.S.) law restricts this device to sale by or on the order of a physician.