TheraSphere is a registered trademark of Theragenics Corporation used under license by Boston Scientific Medical Device Limited, a wholly owned indirect subsidiary of Boston Scientific Corporation.
TheraSphere™ Y-90 Glass Microspheres
Designed for control to achieve durable outcomes, TheraSphere is a targeted radioembolization therapy made of glass microspheres containing radioactive Yttrium-90 (Y-90). TheraSphere is uniquely engineered to have unmatched radiation per microsphere (RPM) to maximize dose to tumor and minimize dose to healthy tissue.
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- Overview
- Clinical data
- Technical specifications
- Ordering information
- Dosimetry software
- Training
- Resources
Most studied, evidence-based Y-90 therapy
TheraSphere preserves quality of life and provides reproducible results for treating and referring physicians. Backed by positive level 1 clinical evidence, TheraSphere remains the only FDA-approved Y-90 therapy for HCC.
TheraSphere mechanism of action explained
Unique, optimal design for tumor control
- The only Y-90 microsphere with radiation embedded throughout
- Maximizes radiation per microsphere (RPM) while minimizing risk of stasis or reflux
- Arrives in a personalized, sealed source vial with easy and safe set-up
- Dose vial administration takes less than five minutes
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Durability leads to quality of life
TheraSphere delivers durable patient outcomes and reproducible results to you and your multi-disciplinary team, while also preserving patient quality of life.
Clinical data since 1999 shows TheraSphere is a proven, evidence-based therapy across different HCC stages, with more than 100,000 patient treatments globally.
Reproducible results backed by Dosimetry Steering Committee recommendations
Key updates from an international multidisciplinary working group provide dosing recommendations based on contemporary clinical data, including results from TheraSphere landmark studies LEGACY, TARGET and DOSISPHERE-01 Trial.
Product details
- Pure beta emitter
- Average energy of 0.9367 MeV
- Average tissue penetration range of 2.5 mm
- Available personalized doses: 3 – 20 GBq (in 0.5 GBq increments), ranging from 750,000 to 5 million microspheres
- Insoluble glass microspheres with a mean diameter of 20-30 µm
- Y-90 is an integral constituent of the glass
Ordering information
Current TheraSphere Customers
TheraSphere Now online ordering platform
This free cloud-based platform provides real-time inventory viewing, dose and accessory ordering, delivery tracking, and more!
If you do not wish to use TheraSphere Now, please proceed to this online order form.
Need a printed copy for your patient files? Please download the PDF to your computer, fill out the form, and submit directly to TherasphereCustomerSupport@bsci.com.
First Time Ordering TheraSphere?
If this is your first time ordering TheraSphere, please note that our Customer Service team requires a completed Customer Information Form prior to account set up.
Please download the PDFs to your computer, fill out the form and submit to our Customer Service team:
Simplicit90Y™ Personalized Dosimetry Software
Simplicit90Y is a customized, easy-to-use dosimetry software developed as an accessory to TheraSphere™ Y-90 Glass Microspheres. Simplicit90Y can help accelerate treatment planning and improve Y-90 Selective Internal Radiation Therapy (SIRT) workflow. Simplicit90Y enables physicians to quickly embrace TheraSphere personalized dosimetry and effectively advance clinical practices with dedicated tools and features.
Design details
Simplicit90Y is a comprehensive software solution for dosimetry planning, allowing you to:
Enhance consistency and efficiency
Simplicit90Y allows you to easily incorporate multimodal images with a range of high-performance registration tools, all with one common interface. Coupled with automated and semi-automated tools for segmentation, this reduces inter-user variability and improves dosimetry consistency and planning confidence.
Analyze with ease
Manipulate your data and expedite analysis with tools for the following:
- Image-based (2D, 3D) dosimetry assessment
- Rapid LSF calculation
- Advanced image registration quality control tools
Confirm Y-90 treatment quality
Simplicit90Y provides the capability to visualize prospective dose distribution and assess the absorbed dose delivered to structures of interest. By allowing for pre- and post-treatment dosimetry, this software can help determine the effectiveness of a patient’s Y-90 SIRT with confidence.
Personalize dosimetry
Simplicit90Y can be used to interactively tailor the absorbed dose per perfused volume by adjusting the injected activity. The software tools can be customized to a patient’s specific tumor presentation and anatomy.
Resources
Training resources to advance your Y-90 investment
Online medical training and education courses
The EDUCARE online platform makes healthcare education and training more relevant, more comprehensive, more personal, and more accessible. Register to access a library of procedural videos, case studies, training resources, and events.
Committed to your cause
From clinical data downloads and data presentation templates, to patient education, practice support and reimbursement resources, we are committed to helping support your Y-90 program.