Skip to main content

My account

Boston Scientific accounts are for healthcare professionals only.

Create an account to access online training and education on EDUCARE, manage your customer profile, and connect with customer support and service teams.

My Boston Scientific account

Access your online applications and manage your customer profile.

Manage my Boston Scientific account

Quick Links

Contact a representative Online education and training Order products online Reimbursement resources Return a product Customer support

Call customer care

1 (888) 272-1001

SYNERGY MEGATRON™

Everolimus-Eluting Platinum Chromium Coronary Stent System

play icon
Introducing SYNERGY MEGATRON
play icon
Introducing SYNERGY MEGATRON
SYNERGY MEGATRON Stent Design Image
SYNERGY MEGATRON Tapered Vessels Image
Introducing SYNERGY MEGATRON

A New Type Of Stent

The SYNERGY MEGATRON Stent System is purpose built for large proximal vessels so you can maximize performance where it is needed most.

Receive Updates
icon_document.png

Directions for Use

 icon_document.png

Indications, Safety, and Warnings

 icon_computer.png

Modern PCI Treat Portfolio

Explore

Best-in-Class Axial & Radial Strength
Unmatched Overexpansion Range
Maximum Visibility
Uniform Lesion Scaffolding
Indicated for Treatment of STEMI Patients​
Indicated for Use in High Bleeding Risk Patients
Ordering Information
 

Best-in-Class Axial & Radial Strength

Overall Strength in Perspective*
Overall Strength In Perspective* Graph

Axial Strength
To maintain stent integrity in complex interventions.

Radial Strength
To maintain vessel patency.

43% more axial strength to maintain stent integrity in complex interventions, 40% more radial strength to maintain vessel patency

All trademarks are property of their respective owners.
* Based on bench test data comparing to largest nominal diameter; 4.0 mm for Xience Sierra and 5.0 mm for SYNERGY MEGATRON and Onyx Frontier. N=3 minimum. Data on file. Bench test results not necessarily indicative of clinical performance.

† SYNERGY MEGATRON 5.0 mm diameter vs. Onyx Frontier 5.0 mm diameter. (N=3 minimum). Bench tests performed by Boston Scientific Corporation. Data on file. Bench test results not necessarily indicative of clinical performance.

 

Unmatched Overexpansion Range

Accommodate Wide Diameter Mismatch
A versatile stent model that can expand 2.5 mm, from 3.5 mm to 6.0 mm, to accommodate wide diameter mismatch.
 
Accommodate Wide Diameter Mismatch Graph

‡ Expansion information pulled from individual DFU documents for: SYNERGY MEGATRON Stent System, SYNERGY XD Stent System, Onyx Frontier Stent System, Xience Skypoint Stent System, Orsiro Mission Stent System.

 

Maximum Visibility

Platinum Chromium (PtCr) Alloy
Enhances visibility to aid in accurate stent placement.
Maximum Visibility

§ 3.5 mm stent products tested under 6.0 mm copper phantom to stimulate body mass. Bench testing performed by Boston Scientific Corporation. Data on file. Bench test results not necessarily indicative of clinical performance.

 

Uniform Lesion Scaffolding

Maximize Lumen Gain
12-peak design minimizes tissue prolapse and maintains lumen diameter.
33% less tissue prolapse, 12-peak stent design to minimize tissue prolapse and maintaine lumen diameter

†† Compared to a 9-peak prototype DES. Bench testing performed by Boston Scientific Corporation. Data on file. Bench test and computational model results may not necessarily be indicative of clinical performance.

 

Indicated for Treatment of STEMI Patients​

FDA APPROVED STEMI INDICATION BADGE
 

STEMI patients have a high risk of subsequent adverse events, so early healing is critical in culprit lesions.¹ SYNERGY is uniquely designed with thin, rounded Platinum Chromium (PtCr) struts, optimized Everolimus drug delivery, and a fast-absorbing, abluminal bioabsorbable polymer to enable early healing. ​​

As the only commercially available DES indicated for treatment of STEMI patients, the SYNERGY platform provides confidence, even in emergency situations.

CLEAR SYNERGY Stent Registry

Evaluated the clinical safety and efficacy of SYNERGY in STEMI patients (n=733).²

4.8% MACE*

vs. 9.45% ​performance goal

 

0.8%

TLR​

 

1.1%

ST

(0.3% ST within 24 hours)​

 
 

*Defined as the composite of cardiovascular death, recurrent MI, or unplanned ischemia-driven target vessel revascularization.

1. Buccheri S, et al. EuroIntervention. 2018;14:e562-e569.

2. Jolly, Sanjit S. et al. J Am Coll Cardiol. 2024;220:111-117.

 

Indicated for Use in High Bleeding Risk Patients

Leading on Studying Short DAPT

The SYNERGY MEGATRON BP Stent can be safely used in conjunction with shortened DAPT in patients at high risk for bleeding (HBR), based on the results from the EVOLVE Short DAPT Trial.‡‡ This trial data, in conjunction with the HBR indication, provides important evidence to inform decisions about DAPT duration for this patient subset.

 


High Bleeding Risk Indication stamp

EVOLVE Short DAPT Trial‡‡ 3

Studying 3-month DAPT in high bleeding risk patients
 
Learn More
 

‡‡ EVOLVE Short DAPT is a prospective, multicenter, single-arm trial defining the safety of 3-month DAPT in subjects at high risk for bleeding undergoing PCI with the SYNERGY BP Stent. Approximately 74% of patients enrolled discontinued DAPT at 3-months. N=1,396 (patients with respective event or sufficient follow-up). Co-primary endpoints: ARC Def/Prob ST and Death/MI from 3-15 months. High risk bleeding subjects were defined as meeting one or more of the following criteria: ≥75 years of age and, in the opinion of the investigator, the risk of bleeding associated with >3 months of DAPT outweighs the benefit; need for chronic or lifelong anticoagulation, history of major bleeding (severe/ life threatening or moderate bleeding based on the GUSTO classification) within 12 months of the index procedure; history of stroke (ischemic or hemorrhagic); renal insufficiency (creatinine ≥2.0 mg/dl) or failure (dialysis dependent); platelet count ≤100,000/μL.

3. Kirtane AJ, et al. Circ Cardiovasc Interv. 2021;14:e010144. doi:10.1161/CIRCINTERVENTIONS.120.010144

 

Ordering Information

ø(mm)8121620242832

Overexpansion 

Capabilities

3.50 H7493942808350H7493942812350 H7493942816350H7493942820350H7493942824350H7493942828350H74939428323506.0
4.00H7493942808400H7493942812400H7493942816400H7493942820400H7493942824400H7493942828400H74939428324006.0
4.50H7493942808450H7493942812450H7493942816450H7493942820450H7493942824450H7493942828450H74939428324506.0
5.00H7493942808500H7493942812500H7493942816500H7493942820500H7493942824500H7493942828500H74939428325006.0
 
 
 
Mega Strength

Mega Strength

Learn why we created a stent purpose-built for large proximal vessels.

Button
Optimal Healing

Optimal Healing

Find out how synchronous drug elution and polymer absorption enables early healing.

Button
SYNERGY Clinical Overview

SYNERGY Clinical Overview

Discover the clinical evidence on the SYNERGY™ BP Stent, including multiple short DAPT studies.

Button
 
MPCI banner
 
Top