MANTIS™ Clip

MANTIS™ Clip designed for defect closure 

With proprietary TruGrip™ anchor prongs 

MANTIS Clip is purpose-built for closing large defects1 in the GI tract

Trying to close large defects in the GI tract can be challenging. Achieving efficient, effective defect closure calls for a purpose-built device, like MANTIS Clip (abbreviated as MANTIS), which enables tissue apposition and closure less than 3 centimeters.2,3

MANTIS: First-of-its-kind device 

Mantis Clip animation

MANTIS is deliberately designed for closing large (< 3cm) defects and allows for a novel approach to achieve tissue apposition less than 3 centimeters independent of jaw opening width.2,3


Closure with minimal slips2,3,4

A three-step approach for closure

You shouldn’t have to settle when it comes to placement, rotation and achieving complete closure. The MANTIS Clip (abbreviated as MANTIS) three-step Anchor, Mobilize, Close approach offers the user the ability to dictate the closure approach for a specific lesion less than 3cm, with minimal slippage.2,3,4

Explore a novel approach to defect closure

Watch how MANTIS allows physicians to approximate across large defects1,2,3 an alternative to using a traditional “zipper” technique2 with conventional clips.


1. Liaquat, H., Rohn, E., & Rex, D. K. Prophylactic clip closure reduced the risk of delayed postpolypectomy hemorrhage: Experience in 277 clipped large sessile or flat colorectal lesions and 247 control lesions. Gastrointestinal Endoscopy, 2013, 77(3):,401–407. https://doi.org/10.1016/j.gie.2012.10.024

2. Boston Scientific conducted a bench study to gather feedback from 16 paid physicians on the use of commercially representative MANTIS™ Clips on excised porcine stomach model and synthetic tissue model. Data on file. The objective of the study was to evaluate MANTIS Clip’s tissue apposition and mobilization design features as compared against Boston Scientific Resolution™ 360 Clips, and other competitive clips. The bench study was performed with minimal training via some preparation in the ex-vivo model. Bench testing results may not necessarily be indicative of clinical performance.

3. The pre-clinical testing was performed by BSC. Data on file. Sixteen paid physicians used MANTIS with anchor, mobilize and close approach on porcine model. Pre-clinical study may not necessarily be indicative of clinical performance.

4. The testing was performed by BSC. Data on file. Bench testing results may not necessarily be indicative of clinical performance. 

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CAUTION: The information presented in this document by Boston Scientific is intended for healthcare professionals in India. The information presented in this document is intended to provide balanced, scientific, and evidence-based answers to unsolicited medical questions.] The information should not be, however, treated as comprehensive and does not intend to provide diagnosis, treatment or any medical or health advice. For full information about the product, please refer to the appropriate product labeling. Responsibility for patient care resides with the healthcare professional on the basis of his or her professional license, experience and knowledge of the patient. Healthcare professionals must rely on their judgment when deciding which treatments and procedures to use with patients.